As shown in Table 2, the univariate analysis results of factors associated with clinical outcomes suggested that age, ALT level, AST level, Lymphocyte count, Neutrophil count, gender, HBV infection, tumor number, BCLC stage, extrahepatic expand, cirrhosis, ascites, AFP level, and ECOG were not significant predictors for PFS(P>0.10). This evidence concerns the gene AFP and Cirrhosis.