Yanghe Pingchuan granules were confirmed to attenuate asthma airway remodeling in a dose-dependent manner by reducing the expression of phosphoinositide 3-kinase (PI3K) and proliferating cell nuclear antigen (PCNA), blocking the PI3K/PKB signalling pathway, suppressing the abnormal proliferation of ASMCs, and alleviating the symptoms of kidney yang deficiency [41]. Here, PCNA is linked to asthma.