PKD2 and ciliopathy: To explore whether the electrical activity of the primary cilium may be linked to ciliopathies, LLC-PK1 cells were transfected with siRNA of the PKD2 gene (siPKD2) as recently reported, which inhibits expression of the polycystin-2 (PC2) channel, and lengthens primary cilia in these cells (Scarinci, et al., 2022).