The study found significant protein expression differences between patients with and without ABI. Patients with severe intracranial hypertension or death had higher GFAP expression than those without. Differences in protein expression were also found between patients with traumatic and nontraumatic ABI, with some proteins related to structural damage, complement activation, and cholesterol metabolism. However, no significant differences were found in protein expression between patients with SAH versus TBI or between those with good versus poor 3-month Glasgow Outcome Scale score. The gene discussed is GFAP; the disease is intracranial hypertension.