AKT1 and diabetic kidney disease: [110], the podocyte injury pathways in DKD are mainly focused on PI3K/AKT signaling pathway, mTOR pathway, JAK/STAT pathway, TGF-β/Smad pathway, Wnt/β-Catenin pathway, MAPK pathway, inflammatory response, oxidative stress, etc. That is similar to our results of NACs on podocytes’ injury, which were almost involved in the regulation of inflammation, oxidative stress and autophagy.