In subsequent years, structures of tau filaments from PiD (Falcon, Zhang, Murzin, et al., 2018), CTE (Falcon et al., 2019), CBD (Arakhamia et al., 2020; Zhang et al., 2020), PART (Shi, Murzin, et al., 2021), AGD, PSP and GGT (Shi, Zhang, et al., 2021) were determined, giving rise to a structure-based classification of tauopathies (Figure 3; Shi, Zhang, et al., 2021). Here, MAPT is linked to tauopathy.