It is well-documented that human serum albumin (HSA) is a desired drug delivery carrier [28–30] due to its unique properties, such as being endocytosed and transcytosed into and across the cell via receptors [29], long half-life of 19 days [31–34], able to accumulate at the tumor tissue due to the enhanced permeability & retention (EPR) effect; and being preferentially taken up and metabolized by cancer cells to serve as nutrients [35–39]. This evidence concerns the gene ALB and cancer.