Upregulation of N-acetyltransferase 10 (NAT10) promotes cancer progression by inhibiting ferroptosis via N4 acetylation and stabilization of FSP1 mRNA in CRC cells.178 FSP1 mRNA undergoes N4-acetylcytidine (ac4C) modification, leading to inhibition of ferroptosis. The gene discussed is NAT10; the disease is colorectal carcinoma.