PECAM1 and neoplasm: To understand whether the inhibitory effect of DYB‐03 could be attributed to angiogenic disruption, histological analysis of tumor tissue was performed to detect the expression of CD31, a marker of microvascular density.[47] CD31 was significantly inhibited in the DYB‐03–treated group compared to the control group, suggesting that DYB‐03 partially inhibited tumor growth through its antiangiogenic effect (Figure 5E).