First, eight S40 subunit proteins (RPS2, RPS3, RPS7, RPS9, RPS13, RPS15, RPS24, and RPS25) and five S50 subunit proteins (RPLP0, RPL11, RPL14, RPL22, and RPL27) were significantly increased in CRC. Here, RPLP0 is linked to colorectal carcinoma.