NEIL2 and COVID-19: Given that NEIL2 is an anti-inflammatory protein33,36 and that the expression of NEIL2 is significantly downregulated in patients with severe COVID-19 and in CoV-2-infected hamsters, we hypothesized that recombinant NEIL2 (rNEIL2) could be used as a modality to counteract CoV-2-infection and its associated inflammatory responses.