The correlation scatter plots indicated that RP11-414H17.5 had positive correlation with genes promoting osteosarcoma metastasis (as for instance ALDOA, EZH2, IRS1, CUL1, EZR, DNMT1, etc.), and negatively correlated with the osteosarcoma metastasis suppressor gene, TNFSF10, suggesting that RP11-414H17.5 is probably a promoter of osteosarcoma metastasis. The gene discussed is EZH2; the disease is osteosarcoma.