The correlation scatter plots indicated that RP11-414H17.5 had positive correlation with genes promoting osteosarcoma metastasis (as for instance ALDOA, EZH2, IRS1, CUL1, EZR, DNMT1, etc.), and negatively correlated with the osteosarcoma metastasis suppressor gene, TNFSF10, suggesting that RP11-414H17.5 is probably a promoter of osteosarcoma metastasis. This evidence concerns the gene CUL1 and osteosarcoma.