In the context of MLL-AML, significant differences were observed in elevated abundance of PCs ((P-38:4)/PC(O-38:5) by 252%), sterol (ST 24:1;O4;S by 154%) and cortisol (by 105%), with decreased abundance of citric acid (by 97%) and PC ((34:5) by 92%) (Supplementary Table 9). Here, KMT2A is linked to acute myeloid leukemia.