Analysis of correlations between D7 and D30 levels of the same biochemical elements and the severity and outcome of stroke on D90 revealed negative correlations between D7 TAC and D90 NIHSS (r: − 0.318; p: 0.028) and between D30 thrombospondin-2 and D90 mRS (r: − 0.336; p: 0.045) scores. The gene discussed is THBS2; the disease is stroke disorder.