SOCS2 and hepatoblastoma: To explore the underlying biological function of SOCS2 in hepatoblastoma, we first detected the mRNA expression levels of SOCS2 in HB cells (Huh6, HepG2) and hepatocytes LO2 by qRT-PCR, and the results showed that SOCS2 was significantly lower in HB cells than in LO2 cell line (Fig. 3A).