Complications were more likely to be associated with larger tumor size, adrenal primary tumor, Shimada classification as NB, presence of IDRFs, high stage of INRG staging system (INRGSS), high-risk group of INRG, MYCN amplification, retroperitoneal lymph node metastasis, laparotomy surgery, long period of operations, GTR, and vascular encasement. The gene discussed is MYCN; the disease is neoplasm.