For the SCD group, there was a separation of the treatment groups within the first three PCs, with a very clear effect of VPA across PCs 2 and 3 [perfect separation of the groups along PC2 + 3, p = 1.7e-13], and an orthogonal effect of TGFβ [PC2–3, p = 1.6e-6]. Here, TGFB1 is linked to Schnyder corneal dystrophy.