For some patients, multiple cultures were derived from distinct sections of the intestine and each of these cultures were treated as independent as reported.17 Multivariate and univariate approaches determined the effects of fibroblast origin [SCD or NSCD], and the effects of treatments [TGFβ and VPA], as well as the interactions between them. This evidence concerns the gene TGFB1 and Schnyder corneal dystrophy.