MECP2 and Rett syndrome: Signs of severe epilepsy have also been identified in Mowat–Wilson syndrome, which is caused by a violation of the expression of the SIP1 gene [65], Rett syndrome, which is caused by a violation of MECP2 [66], and Satb2-associated syndrome, which occurs when the expression of the transcription factor SATB2 is disrupted [67].