PGE1 also enhances migration and invasion in other types of cancer, such as hepatocellular carcinoma or non-small cell lung cancer, by upregulating the expression levels of Snail, a key inducer of epithelial–mesenchymal transition (EMT) [62,63], known to inhibit the expression of E-cad [64]. The gene discussed is CDH1; the disease is non-small cell lung carcinoma.