IL6 and gastric cancer: Overall, independently of the adopted proteomics approach, analyses investigating the same target showed concordant results: plasma HLA-G levels were higher in GC patients compared with those of individuals affected by benign gastric disease or healthy subjects [43,50], serum IL-6 was more abundant in GC patients [55,56,70], and PD-1 content was lower in GC compared with controls [45,61].