CRP and gastric cancer: In a cohort of 219 patients infected or not by H. pylori and suffering from mild to advanced gastritis and ulcers, considered as pre-malignant conditions, and early to advanced GC, using label-free comparative proteomics with LC-MS/MS, Aziz et al. [52] found two serum protein marker panels associated with early or advanced GC independent of H. pylori infection, with 29 (i.e., integrin-6 and glutathione peroxidize) and 10 (i.e., CRP, protein S100A9, and kallistatin) proteins, respectively, which were proposed for the further development of multi-protein assays for GC serum diagnostics.