HLA-G and cancer: Higher HLA-G levels in GC patients (n = 81) than in patients with benign gastric disease (n = 53) and normal controls (n = 77) were also observed by Pan et al. [50], who also proposed detecting sHLA-G with other cancer markers (CA125 + CA19-9 + sHLA-G or CA125 + CA724 + sHLA-G) for the diagnosis of GC.