To check the direct effects of the inhibitory agents on the isolated GBM cell line S635, a spheroid migration assay was performed, where the small molecules danirixin and navarixin and the blocking non-directional CXCR2-overstimulation showed no effect on migration; in combination with dexamethasone, less migration was seen in the condition with CXCL2 overstimulating treatment (see Figure 4a). The gene discussed is CXCR2; the disease is glioblastoma.