In a study conducted by Kim et al., in which murine HCC models were given a single dose of 10 Gy RT followed by four injections of anti-PD-L1 administered in 3-day intervals post-RT or either treatment alone, the combination arm revealed significant tumor growth suppression compared to the other groups and a significantly higher 7-week survival rate (90% in the combination group vs. 30% in the radiation group vs. 0% in the anti-PD-L1 group; p < 0.001) [101]. Here, CD274 is linked to neoplasm.