For example, Zhou et al. demonstrated that the regulation of the C—C motif chemokine ligand 5 (CCL5)—mediated c—Jun N—terminal kinase (JNK) and nuclear factor—kappa B (NF—κB) pathways is involved in mitigating symptoms of LPS—induced pneumonia in an in vitro model [22]. The gene discussed is MAPK8; the disease is susceptibility to pneumonia measurement.