Propolis reduces mitochondrial membrane potential and changes the expressions of specific tumor suppressors (miR-34, miR-15a, and miR-16-5p) and carcinogenic (miR-21) miRNAs by increasing the levels of proapoptotic proteins (p21, Bax, p53, p53 Ser46, and p53 Ser15) in the MCF-7 cell line [14]. This evidence concerns the gene TP53 and neoplasm.