AMBN and periodontitis: Current treatments for aggressive periodontitis include the access surgery (modified Widman flap procedure), as well as the employment of different regenerative techniques, such as (i) bone grafting (autografts, allografts), (ii) guided tissue regeneration (GTR) using non-resorbable and resorbable membranes, and (iii) biological modifiers (enamel matrix proteins) [25,26].