MT-ND1 and Leber hereditary optic neuropathy: Noteworthy, La Morgia and colleagues reported an association between a rare variant (m.4171C>A) in MT-ND1, causing Leber’s hereditary optic neuropathy (LHON) and bilateral brainstem lesions together with vomiting and vertigo, in addition to the typical feature of LHON [32].