Genome-wide association studies (GWAS) on suicide attempts in BD patients have found a trend of association with rs2767403, an intron variant of the Aminopeptidase O (AOPEP) gene, which encodes a metalloprotease linked to the renin-angiotensin system, and strong support for the chromosome 4 locus in LOCI105374524, a non-coding RNA of the glucosylceramidase beta 3 (GBA3) gene [33]. Here, AOPEP is linked to Behcet disease.