It has been proven that persistent VTX exposure leads to the upregulation of different pro-survival Bcl-2 family members, such as BCL-XL, MCL-1, and BCL2-A1 [27,48,76,105,106,107], which have been found to be overexpressed in many hematologic malignancies and other cancers [108,109]. Here, BCL2 is linked to cancer.