CYP19A1 and polycystic ovary syndrome: In fact, when we compared the mRNA abundance of steroidogenic enzymes in GCs of PCOS and control women, we did not observe modifications in the mRNA abundance of CYP19A1 in PCOS GCs, as reported by others [44], which is in line with the unchanged intracellular E2 content between the control and PCOS groups.