PAX4 and MODY: However, there are more mutations also associated with MODY, responsible for many metabolic actions, such as ATP binding cassette subfamily C member 8 (ABCC8), B-lymphocyte kinase (BLK), carboxyl ester lipase (CEL), neurogenic differentiation 1 (NEURO1), paired box 4 (PAX4), pancreatic duodenal homeobox (PDX), and others.