Furthermore, white adipocytes crosstalk in a paracrine manner with breast cancer cells through these adipocyte-secreted factors, which not only increases the risk of developing breast cancer due to hormone conversion, mediated through aromatase in post-menopausal woman, but also facilitates breast cancer cell migration and invasion away from the localized tumor [4,5,6,8,32,34,35]. This evidence concerns the gene CYP19A1 and breast carcinoma.