Luteolin enhanced the TRAIL sensitivity of NSCLC cells (A549 and H1975) but not of the human normal lung epithelial cell line Beas-2B through a mechanism involving the upregulation of DR5 expression and dynamin-related protein 1 (Drp1)-dependent mitochondrial fission [49]. Here, TNFRSF10B is linked to non-small cell lung carcinoma.