CRP and age: ‘Inflamm-aging’ is the term coined to depict the link between inflammation and age-dependent inflammatory diseases that describes a low-grade chronic and sterile inflammatory state assessed in elderly though the detection of high level of circulating pro-inflammatory mediators, such as interleukin IL-1β, IL-6, TNF-α, and C-reactive protein (CRP) [59,60,61], useful biomarkers of innate immune system chronic activation [60,61].