To sum up, the findings from the selected anti-inflammatory and anti-migraine drugs, including acetylsalicylic acid, zolmitriptan, paracetamol, a combination of acetylsalicylic acid with paracetamol and caffeine, ibuprofen, and sumatriptan, did not demonstrate any inhibitory effects on the activity or levels of DAO, both in in vitro experiments and in human enterocytes cultures. The gene discussed is DAO; the disease is migraine disorder.