TRIM21 and interstitial lung disease: Previous studies that investigated ILD clinical associations and predictors reported that older MCTD patients and those presenting Raynaud’s phenomenon, dysphagia, elevated C-reactive protein (CRP), anti-Ro52 autoantibodies, and giant capillaries in nailfold capillaroscopy had a higher prevalence of ILD [5,6,7,8,9,10].