In the global survey (2021) of the World Federation of Haemophilia (WFH), 117 National Haemophilia Associations reported a total number of 256,840 PwH, 185,318 with HA (3.39% being females), and 37,998 with HB (5.53% being females) [9]. The gene discussed is GSTM1; the disease is hemophilia.