Unfortunately, there are many challenges posed with obtaining a clear diagnosis from cytology, one being that many procedures such as transduodenal and transgastric approaches during EUS FNA sometimes cause GI contamination and background mucin, leading to misdiagnosis of the SCA as a mucinous cyst such as IPMN or MCN. Here, MUC5AC is linked to pancreatic intraductal papillary-mucinous neoplasm.