HDAC1 and familial pancreatic carcinoma: As shown in Figure 5, the authors demonstrated the potential of multi-functionalized monolayer GO as a gene delivery platform to co-deliver HDAC1 and K-Ras siRNAs (small interfering RNAs targeting the HDAC1 gene and the G12C mutant K-Ras gene, respectively) to specifically target pancreatic cancer cells.