CHAT and Alzheimer disease: Shangchong et al. [51] revealed that ginsenoside Rg2 significantly enhanced the learning memory ability of scopolamine-induced AD mice, and the mechanism may be related to the inhibition of acetylcholinesterase (AChE) activity and the increase in choline acetyltransferase (ChAT) activity in the hippocampus and pre-cortex of mice.