Interestingly, there is an increase in the IncRNA myocardial infarction-associated transcription (MIAT) allele in patients with DCM, which has also been proven to regulate caspase-1/GSDMD-mediated pyroptosis in vivo and in vitro by targeting miR-214-3p in DCM [99]. The gene discussed is CASP1; the disease is familial dilated cardiomyopathy.