Gypenosides, which are the main components of Gynostemma pentaphyllum, can inhibit ROS-induced activation of the NLRP3 inflammasome caused by cytochrome c, improve myocardial cell injury in H9c2 cells, and inhibit the development of DCM in vivo [126]. This evidence concerns the gene NLRP3 and familial dilated cardiomyopathy.