ABCB1 and laryngeal carcinoma: For instance, Schmidt et al. [53] studied the in vitro effect of G. verum L. aqueous extract on chemosensitive laryngeal carcinoma cell lines (Hep-2 and HLaC79) and on chemoresistant laryngeal carcinoma cell lines with P-glycoprotein overexpression (Hep2-Tax, HLaC79-Tax), where they highlighted an effect of inhibiting the growth of both types of cell lines.