ESR1 and Infertility: In another study [17], a computational approach was used to compare the effectiveness of reported bioactive chemicals in plant hemp towards three proteins associated with male fertility (i.e., 24-dehydrocholesterol reductase (DHCR24), cation channel sperm associated 1 (CatSper 1), and testis expressed protein 11 (TEX 11)) with clomiphene, a particular estrogen-receptor stipulated for the medical management of infertility.