In MC-38 tumor grafts, using the same experimental set-up as in RM-9, radiation increased mRNA levels of CXCL1, CXCL2, CXCL3, and CXCL5 at 24 h post-treatment (Figure 4D) and protein levels of CXCL5 at 24 h and 48 h post-treatment (Figure 4E). The gene discussed is CXCL2; the disease is neoplasm.