ITGA6 and cancer: Interestingly, the repression of ITGA6 (Integrin Alpha-6) and ITGA9 (integrin signaling pathways) in GBM cells by KLF9 resembles the repression of ITGB8 gene by KLF9 in endometrial cancer cells [31]; thus, KLF9 may broadly function as a repressor of specific cell–cell and cell–extracellular matrix interactions between cancer cells.