Dose-dependent NDV-D90 cytotoxicityNDV-D90 with higher replication and anti-tumor effect in low differentiated, highly proliferative GC (p < 0.05 for SGC7901 and BGC823 vs. MKN28)NDV-D90 significantly impairs GC vascularization, demonstrated objectively by VEGF-A and MMP-2 levels (p < 0.05). This evidence concerns the gene MMP2 and neoplasm.