T-01 had minimal tumor growth compared to PBS control group (7× tumor growth, p < 0.01), but T-TSP-1 had significant tumor growth inhibition even compared to T-01 (p < 0.05)Enhanced cytotoxicity of T-TSP-1 compared to T-01 in vitro for some GC lines, possible from signal transduction of α3β1 integrin. This evidence concerns the gene THBS1 and gastric cancer.