AKT1 and ovarian carcinoma: Moreover, the STAT3 ODN-decoy caused a reduction in the level of the extracellular matrix metalloproteinase inducer (EMMPRIN), a marker of ovarian cancer metastasis, P-glycoprotein (P-GP), and phosphorylated RAC-alpha serine/threonine protein kinase (p-AKT) proteins, which are responsible for chemoresistance in ovarian cancer cells [169].