TTFields cause the release of micronuclei from the nucleus into the cytoplasm by inducing the focal disruption of the nuclear membranes of glioblastoma cells, where the micronuclei activate and recruit the stimulator of interferon genes (STING), which are absent in melanoma2 (AIM2)/caspase1 inflammatory vesicles. The gene discussed is STING1; the disease is glioblastoma.