In contrast to this notion, two bioinformatics studies on data sets from the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) have revealed that claudin-low breast cancers can be stratified along with other intrinsic subtypes (e.g., luminal A, luminal B, HER2-enriched) [98,107], meaning that diverse epithelial cell types may give rise to CLBC. The gene discussed is ERBB2; the disease is breast cancer.