Consistent with these findings, we observed an increase in hematopoietic progenitors expressing H3K27me3 in GATA2-EB patients compared to GATA2-RCC patients (the proportion of H3K27me3-positive progenitors mean ± SD in GATA2-EB was 0.1512 ± 0.05944 versus 0.05063 ± 0.01921 in GATA2-RCC, p < 0.01, Figure 3F). This evidence concerns the gene GATA2 and epidermolysis bullosa.