A study conducted by Lim et al. identified decreased levels of cell cycle and myogenic-associated markers of muscle atrophy, like Myogenin, myoblast determination protein 1 (MyoD), paired box protein 7(Pax7), and Cyclin D1 in tumor-bearing mice before the onset of weight loss, suggesting that muscle atrophy caused by decreased muscle regeneration might be initiated at the onset of neoplastic processes [1]. The gene discussed is MYOD1; the disease is neoplasm.